Endocrine Abstracts

Introduction: Artifactual hypoglycaemia has been reported to occur in leukaemia, and also reported in polycythemia Vera, being caused by in vitro autoglycolysis due to an exaggerated consumption of glucose by white blood cells1. We report a case of recurrent hypoglycaemia found to be artifactual secondary to a leukamoid reaction.Case report: A 78-year-old lady with a poorly differentiated endometrial adenocarcinoma was referred to us with a hi...

Gitelman’s syndrome (GS) is an autosomal recessive primary renal tubular disorder with hypokalemic metabolic alkalosis, hypocalciuria, and magnesium deficiency. The association of GS and type 1 diabetes is rare1, and bilateral hydronephrosis and hydroureter has not been reported.A 18-year-old female with known GS diagnosed at 17 years of age and type 1 diabetes diagnosed at 15 years of age was admitted to Leicester Royal Infirmary for pre...

Background: Metformin is increasingly used in the management of polycystic ovary syndrome (PCOS) but there remain differences in opinion as to its precise role in terms of clinical benefit. We retrospectively reviewed the effects of metformin on menstrual regularity, fertility, weight and hirsutism in 244 patients with PCOS treated routinely with metformin in our clinics.Results: Patients were of median age 27 years (range 12–47) with median BMI of ...